Did you try to change a mudfish node based on FAQ - Nodes section for your game item? If you're using the advanced mode, please start with the basic mode.

I have been using basic mode, if I used advanced the ping varies a lot.

Any update on this? Have you been able to improve nodes between those 2 locations (if possible). Thanks.

Nop.  :-(  However which mudfish node did you try to use?  Did you test with "US West (Los Angeles - Colo)" node too?

Usually before I use mudfish I will check the RTT avg for lowest ping + best std. Today I used US West (Los Angeles - Aoyou 2), which I believe said 280 (or less), but ingame my ping was never lower than 340. Often it would go up.

Umm.. Then if you're familiar with Command Prompt, could you please ping to 198.20.200.73 IP while mudfish is running?  Is it still different?

Pinging 198.20.200.73 with 32 bytes of data: Reply from 198.20.200.73: bytes=32 time=290ms TTL=51 Reply from 198.20.200.73: bytes=32 time=290ms TTL=51 Reply from 198.20.200.73: bytes=32 time=290ms TTL=51 Reply from 198.20.200.73: bytes=32 time=290ms TTL=51 Ping statistics for 198.20.200.73:     Packets: Sent = 4, Received = 4, Lost = 0 (0% loss), Approximate round trip times in milli-seconds:     Minimum = 290ms, Maximum = 290ms, Average = 290ms

As you can see, it takes 290 ms from your desktop to 198.20.200.73 IP (might be one of game server).  However we need to verify the game server again whether it moves to.  Please send me some game packets using Packet Capture with Mudfish link while playing the game with Full VPN mode if possible.